General Hospital of Komotini "Sismanogleio" is a decentralized and independent service unit providing vital services in the areas of primary, secondary and emergency healthcare, to the citizens of the broader area of the Regional Unit of Rodopi. It has a total capacity of 200 beds, out of which 4 Intensive Care Unit beds. An organized Surgery Department exists, which is comprised of 4 Operating Rooms. The Hospital is comprised of three divisions: Administrative, Medical, Nursery. The number of employees is: 62 Administrative, 88 Medical, 179 Nursery and 52 Medical Operations.

Having administrative and financial autonomy, it is run by a five-member executive committee. President of the committee is the Chief Executive Officer.

The financial resources of the Hospital, comes mainly from public-state grants, with a total annual budget of over 7.000.000€.